Sucralose is a popular artificial sweetener usually sold under the brand name Splenda
According to the findings of a study involving rats, that appeared in the October 2009 issue of "Regulatory Toxicology and Pharmacology," sucralose yielded negative health effects. Researchers found that sucralose interfered with nutrient absorption, increased body weight and decreased the amount of beneficial bacteria in the intestines. A study released by "The Journal of Toxicology and Environmental Health" in January 2008 states that Splenda may alter the composition of the intestinal microflora, the natural micro-organism residents of the intestines that protect against the possible growth of disease-causing organisms. With a decreased number of resident micro-organisms in the intestines, infectious diseases may occur in the gut. In a study published in "The Chinese Journal of Integrated Traditional and Western Medicine" in March 2006, researchers stated that the decrease in the intestinal flora signals the attack of irritable bowel syndrome, a chronic gastrointestinal disorder characterized by abdominal cramping, and bloating.
According to "The Journal of Toxicology and Environmental Health," Splenda may enhance the expression of CYP3A4 cytochrome P450, resulting in the alteration of the availability of certain orally administered drugs such as oral hypoglycemic agents for diabetics, angiotensin II blockers used by hypertensive patients, anti-epileptic medications, beta blockers for hypertension and heart problems, antidepressants, antipsychotics and macrolide antibiotics such as clarithromycin and erythromycin.
Dioxin, one organochlorine compound that is a by-product of the paper bleaching process, is 300,000 times more carcinogenic than DDT, an insecticide that was banned because of its toxicity. These compounds have been linked to birth defects like babies with 2 heads, cancer, and immune dysfunction. These chemicals also stay in your body and accumulate over time. According to the Sucralose Toxicity Information Center, the absorbed sucralose and its metabolites (chemically altered substances) concentrate in the liver, kidney, and gastrointestinal tract. Splenda manufacturers claim there is minimal absorption of Splenda and its metabolites. The FDA says there is only 11% to 27% absorption, but the Japanese Food Sanitation Council says as much as 40% is absorbed by the body. One study on sucralose showed an increase in glycosylated hemoglobin, that results in damage to the oxygen carrying part of a red blood cell. Fat soluble substances, such as DDT, can remain in your fat for decades and devastate your health. Considering that Splenda bears more chemical similarity to DDT than it does to sugar, are you willing to bet your health? Consider this, the only organizations between you and product toxic side effects are the FDA and the manufacturers of sucralose (Tate & Lyle) and of Splenda (McNeil Nutritionals). Now the FDA has a long standing history of ineffective screening and rampant conflict of interests as demonstrated in their inability to identify Vioxx as too dangerous to be on the market. This mistake costs 55,000 people their lives.
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