Arginine
or L-Arginine
has been studied with respect to its role in more than 150 diseases,
but before I get into some of the other health areas, let's first review
what arginine is, and why it's so important for your cardiovascular
health. Once in the body, arginine is converted into another chemical
known as nitric oxide, which can improve blood flow and stimulate the
release of certain hormones, including insulin, and growth hormone.
Arginine was first isolated in 1886. In 1932,
scientists learned that arginine is needed to create urea, a waste
product that is necessary for toxic ammonia to be removed from the body.
In 1939, researchers discovered that arginine is also needed
to make creatine. Arginine is
considered a semi-essential amino acid, because we make some in our
bodies. Every chemical reaction which occurs in the body relies on one
or more of the twenty amino acids we have in our bodies. Amino acids and
in particular arginine, are found in protein rich foods such as meat,
dairy, nuts, beans, and some grains. When an "L" is placed in front of an
amino acid (as it can be for any of the twenty in our bodies) it
indicates that the amino acid can exist in two possible forms: L or D.
Now, D-Arginine is often made for use by research by scientists but is
not sold or used commercially. D-arginine is not found in nature though
it is considered to be the mirror image of L-arginine in terms of its
chemical structure. So, essentially there is no real difference between
L-Arginine and Arginine, unless you are a scientist using D-Arginine.
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- Helps get rid of ammonia: A toxic waste product. Your cells release nitrogen all the time from the normal process of repairing and replacing damaged cells, and this nitrogen combines with hydrogen to form ammonia.
- Assists in producing other amino acids: creatine, L-proline, and L-glutamate. Creatine is important to muscle energy and proper nervous system function. L-proline is important for collagen synthesis and the healing of wounds. L-glutamate is an excitatory neurotransmitter, key to brain function, especially left hemisphere functions (logic and reasoning, language, computational skills, learning and memory).
- Promotes good sexual function: for both men and women. Increased microcirculation in genital tissues results in stronger erections and better sexual responsiveness, by the same nitric oxide mechanism.
- Has endocrine effects: Simply put it promotes the release of two important hormones, human growth hormone (HGH) and prolactin
L-Arginine combined with L-Citrulline's effectiveness has also been studied in combination with
antioxidant supplements, and the results from these studies is even more
dramatic. The introduction of antioxidants to the already powerful
effect of L-Arginine and L-Citrulline allows for these two supplements
to better do their jobs because the antioxidants deactivate or
neutralize the effects of the free radicals in the body, allowing for
the easier production of Nitric Oxide. So, Nitric Oxide production is
the catalyst for improved blood flow and lower blood pressure.
Furthermore, studies have shown that when the body has done a good job
getting rid of a significant amount of free radicals, antioxidants can
then restore the health of the cells that produce Nitric Oxide (the
endothelial cells) and can create a better defense against future
attacks on our immune system.
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- L-arginine and Pycnogenol resulted in significant improvement in sexual function in men with ED, according to this 2003 study. http://www.ncbi.nlm.nih.gov/pubmed/12851125.
- L-arginine and Yohimbine were found to increase sexual arousal in a 2002 study http://www.ncbi.nlm.nih.gov/pubmed/12187545 of postmenopausal women with sexual arousal disorder.
In
terms of dosage, a pilot study published in the Journal European
Urology found 6 grams of arginine combined with 6 mg of yohimbine was
successful in treating men with ED. Nitric oxide is also believed to
play a role in women's sexual function. (Musicki et al, 2009). Since
Nitric Oxide is a gas, you can't just pop a pill to increase your NO
level. You are very dependent on your body's synthesis of this gas from
the raw materials you take in through diet. Make sure you get enough
high quality protein, and a diet rich in organic whole foods that are
loaded with antioxidants, and not pesticides. If you suspect you may be
deficient in arginine, you might consider the added protection of a
supplement, but it is my STRONG recommendation to first try to obtain it
through normal dietary food sources, it is the best way to experience
the benefits of this nutrient. Foods high in protein are also usually
high in arginine. According to the Mayo Clinic, some good animal sources
of the amino acid include meat, chicken and dairy products. Beef flank
steak, for instance, has about 1,200 mg of arginine per 3.5-oz serving,
according to traditionaloven.com. A chicken breast has about 1,000 mg in
the same serving size, while cheddar cheese has about 950 mg. Some of
the foods highest in Arginine are:
- Seeds (sesame, pumpkin, sunflower, poppy, caroway)
- Seaweed (spirulina is an excellent source)
- Nuts (walnuts, almonds, peanuts)
- Coconut
- Eggs and Whey
- Beans
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